Biochemistry is full of metabolic pathways where the end product, or
even sometimes intermediates, inhibits the first or second enzyme in
the pathway. This was always considered to be negative feedback in
every text I've ever seen. So, if I understand you correctly, the
answer is yes. It's a negative feedback homeostatic mechanism.
Harbut, Chester wrote:
On a recent essay exam I asked my students to give
me an example of negative feedback. Most used
parameters such as glucose concentration, temperature, even calcium
concentrtion. Two students however
used "end-product inhibition" of enzymes (with specific examples).
I''m just curious, do most of you
consider this negative feedback in the classical sense?
Thanks
Chet Harbut, Ph.D.
Biology Dept.
Cerritos Community College
11110 E. Alondra Blvd
Norwalk, CA 90650
(562) 860-2451 ext: 2684
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James S. Miller, Ph.D.
Phone:
574-535-7308
Chair & Professor of Biology
Goshen
College
E-mail: JamesSM@xxxxxxxxxx
Goshen IN 46526-4795
USA
Web: http://www.goshen.edu
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