Janet, I'm not sure I understand what you mean by 'moelcular clocks.' I also teach developmental biology and about every 3rd year, 'Biological Clocks and Rhythms.' The molecular clocks that have been studied in many organisms suggest that there are a number of genes at work within the clock, e.g. 'PER' and 'TIM'. These are definitely coding for particular clocking processes, and their genetic loci are known in a number of species. Mutations can produce organisms like 'clockless.' The eclosion rhythm in several Drosophila species has been studied extensively. And less esoterically, the accumulation of cyclins and MPF are likely under these genetic influences. Please explain. Thanks. Bob Robert S. Rawding, Ph.D. Assistant Professor Department of Biology Gannon University 109 University Square Erie, PA 16541 Phone: (814) 871-5872 FAX: (814) 871-5757 ________________________________ From: HAPS-L-owner@xxxxxxxxxxx on behalf of Janet Sherman Sent: Sun 2/18/07 9:12 AM To: HAPS-L@xxxxxxxxxxx Subject: RE: [HAPS-L] Mutations Ken, This is the basis of the molecular clocks. Most mutations are actually 'silent' ________________________________ From: HAPS-L-owner@xxxxxxxxxxx on behalf of Ken Saladin Sent: Sat 2/17/2007 6:00 PM To: HAPS-L@xxxxxxxxxxx Subject: [HAPS-L] Mutations The conventional wisdom is that most mutations are deleterious. But if 98% of the DNA is noncoding (and with certain other assumptions that seem of only peripheral relevance), wouldn't it be more accurate to say that a considerable majority of mutations are harmless? Just a bit of food for thought. Ken ========================================== To manage subscription,send email from the subscription address to imailsrv@xxxxxxxxxxx and in MESSAGE (1) To unsubscribe from HAPS-L, put : unsubscribe HAPS-L, (2)To subscribe from a different address, put : subscribe HAPS-L your_full_name =========================================
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