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[HAPS-L] Viruses and transcription sites



Here's a different DNA-related question. Maybe someone on the list with some microbiology background knows the answer to this.

Presumably a virus wouldn't be replicated if it inserted its genome into a noncoding region of the host DNA. Does viral DNA, therefore, have a way of recognizing transcriptional starter sites such as TATA boxes in the host genome and selectively inserting there, where it "knows" transcription will occur? Are viral insertion sites nonrandom? Or do viral genomes carry their own TATA boxes (or something equivalent) that makes the host RNA polymerase recognize them as transcribable DNA?

Ken